Management of Refractory Menstrual Bleeding in an Adolescent with Glanzmann Thrombasthenia: A Case Report and Review

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clinical management of glanzmann's thrombasthenia: a case report.

glanzmann's thrombasthenia (gt) is a rare, genetically inherited platelet disorder in which the platelet glycoprotein iib/iiia (gp iib/iiia) complex is either deficient or, dysfunctional. the incidence is about 1 in 1,000,000. this case report deals with a 4 year-old girl diagnosed with gt presenting with dental caries and periapical lesions in the primary mandibular first molars. to provide th...

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Glanzmann thrombastenia (GT) is a rare disease of an autosomal recessive inheritance characterized with fatal bleeding tendency. The anaesthesiologist should be cognizant of the risk involved and be prepared with necessary measures. In this paper, we present a GT case of a 9-year-old male with hypospadias, which was successfully repaired after platelet transfusions according to the thromboelast...

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Glanzmann thrombasthenia

Glanzmann thrombasthenia (GT) is a rare autosomal recessive bleeding syndrome affecting the megakaryocyte lineage and characterized by lack of platelet aggregation. The molecular basis is linked to quantitative and/or qualitative abnormalities of alphaIIb beta3 integrin. This receptor mediates the binding of adhesive proteins that attach aggregating platelets and ensure thrombus formation at si...

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Glanzmann thrombasthenia in a neonate.

Glanzmann thrombasthenia is a qualitative platelet function disorder manifested by skin bleeds, epistaxis, gingival bleeding, gastrointestinal hemorrhage, hematuria, hemarthrosis, intracranial hemorrhage and visceral hematomas. We report a six day old newborn presenting with hematuria following suprapubic aspiration, who was diagnosed as Glanzmann thrombasthenia. We believe it to be the younges...

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ژورنال

عنوان ژورنال: Case Reports in Obstetrics and Gynecology

سال: 2020

ISSN: 2090-6692,2090-6684

DOI: 10.1155/2020/8848763